Since BPA has come under pressure from regulators, companies have moved to using other similar bisphenol alternatives, such as bisphenol S, bisphenol F, and bisphenol Z all found to have similar toxic implications and endocrine-disrupting properties.
The structure of the BPA molecule is similar to the body’s natural female sex hormones allowing it to bind and activate the estrogen receptor triggering a cascade of hormone related events. The fact that BPA can mimic oestrogen in this way has been known for decades, but it was initially considered a weak estrogen because of its lower affinity for the estrogen receptors as compared to the major natural estrogen, estradiol (E2).
However, today we know BPA can promote estrogen-like activities that are similar to or stronger than E2 when it acts through the ‘non-classical’ pathways outside the cell nucleus. BPA could advance the timing of puberty, and disrupt menstrual cycles.
Other studies have shown it has the opposite effect on the male sex hormone pathways, inhibiting the binding of androgens which could negatively affect the male reproductive system, including impacts on prostate size and sperm count.
Furthermore, plastics have been associated with an increased risk of breast cancer and correlated with neurological disorder ADHD.
In summary ‘BPA-Free’ is different, but not necessarily better nor safer. Look after yourself and the environment by removing plastics from your lifestyle and opt for glass or steel substitutes wherever possible.